Adult onset pernicious anemia

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Vitamin B 12 deficiency anemiaof which pernicious anemia is a type, [8] is a disease in which not enough red blood cells are produced due to a deficiency of vitamin B Pernicious anemia refers to anemia that results from lack of intrinsic factor. Because pernicious anemia is due to a lack of intrinsic factor, it is not preventable.

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Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. There are many types of anemia.

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An overbearing tiredness that never really goes away. Inability to stand up straight with closed eyes or when it is dark. These are usually experienced in the feet and hands though they can appear anywhere.

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If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus. Vitamin B 12 deficiency resulting from decreased production and availability of intrinsic factor secondary to autoimmune-induced gastric mucosa atrophy. It affects males and females equally.

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Its prevalence is 0. Given its polymorphism and broad spectrum of clinical manifestations, pernicious anemia is a great pretender. Its diagnosis must therefore be evoked and considered in the presence of neurological and hematological manifestations of undetermined origin.

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Most patients present in the first year of life with systemic, hematological, and neurological abnormalities. Late-onset forms are rare and had not been comprehensively characterized. They could be easily misdiagnosed.

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MIFTS : Pernicious Anemia Categories : Metabolic diseases, Rare diseases. Expand all tables.

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Anemia is a medical condition in which the blood is low in normal red blood cells. Pernicious anemia is one of the vitamin B deficiency anemias. Pernicious anemia is a rare condition, with a prevalence of.

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Pernicious anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12, which is essential for the development of red blood cells. Most cases result from the lack of the gastric protein known as intrinsic factor, without which vitamin B12 cannot be absorbed. Recurring episodes of anemia megaloblastic and an abnormal yellow coloration of the skin jaundice are also common. Pernicious anemia is thought to be an autoimmune disorder, and certain people may have a genetic predisposition to this disorder.


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